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Ivet Bahar

 

 

Department of Computational & Systems Biology
School of Medicine, University of Pittsburgh
3064 Biomedical Science Tower 3
3501 Fifth Avenue, Pittsburgh, PA 15213

Voice: 412 648 3332 - Fax: 412 648 3163

bahar@pitt.edu
  http://www.ccbb.pitt.edu


 

 

Current Position

Distinguished Professor and John K. Vries Chair,  Department of Computational and Systems Biology, School of Medicine (SOM), University of Pittsburgh (Pitt)

Associate Director, University of Pittsburgh Drug Discovery Institute

Education

Ph.D. in Chemistry, Istanbul Technical University, Turkey, 1986
M.S. in Chemical Engineering, Bogazici University, Istanbul, Turkey, 1983
B.S. in Chemical Engineering, Bogazici University, Istanbul, turkey, 1980

Career/Employment

Distinguished Professor of Comp & Systems Biol, Dec 2013-present
Associate Director, U of Pittsburgh Drug Discovery Institute, 2010-present
Director/PI, MMBioS, NIGMS Biomed Technol & Res Center,
Joint Center between Pitt, Carnegie Mellon, PSC & Salk Inst, 2012-present
John K. Vries Chair, Dept of Comp & Systems Biol, SOM, Pitt, 2010-present

Co-Director, Clinical & Translational Sci Inst, Mol & Sys Modeling Core, 2010-2012
John K. Vries Chair, Dept of Comp Biol, SOM, Pitt, 2005-2010
Founding Chair, Dept of Comp Biol, SOM, Pitt, 2004-2010
Founding Director, PhD Program in Comp Biol, Pitt & Carnegie Mellon U, 2005-2009
Founding Director, Center for Comp Biol & Bioinformatics, SOM, Pitt, 2001-2004
Professor, Dept of Molecular Genetics & Biochemistry, SOM, Pitt, 2001-2004

Professor, Chem Eng Dept, Bogazici University, Istanbul, 1993-2001
Head, Adv Polymeric Matls Res Unit, TUBITAK, Bogazici U, Istanbul, 1998-2000
Director, Polymer Research Center, Bogazici University, Istanbul, 1992-2000
Fogarty Fellow & Visiting Scientist, Exp & Comput Biol Lab, NCI, 1992-2000 (summers)
Visiting Scientist, NATO & CNRS projects, Ecole Superieure de Physique et Chimie Lab de Physicochimie Struct et Macromol (PCSM), Paris (short-term visits) 1989-1998
Visiting Professor, U of Akron, Inst of Polymer Sci, Akron, Ohio (summers) 1988-91
UNESCO Fellow, U of Akron, Inst of Polymer Science, Akron, Ohio (summer) 1987
Associate Professor, Chemical Engineering Dept, Bogazici U, Istanbul, 1987-93
Assistant Professor, Chemical Engineering Dept, Bogazici U, Istanbul, 1986-87
Research Assistant, Chemistry Dept, Istanbul Technical U, Turkey, 1984-86

Honors and Awards

2016-2020  The Biophysical Society, Awards Committee.
2019  The 2019 Kadir Has Outstanding Achievement Award, Kadir Has University. Award Recipient. Istanbul, Turkey.
2016  Invited Speaker at the White House, Natl Strategic Computing Initiative 1st Year Anniversary
2016  Distinguished Lecturer, TIGP, Academia Sinica, Taiwan (elected by Taiwan International Graduate Program (TIGP) students)
2015  International Society for Computational Biology (ISCB) Senior Member Designation
2014  Chancellor's Distinguished Research Award (U of Pittsburgh)
2013  Distinguished Professor, University of Pittsburgh.
2012-  The Science Academy, Turkey, Principal Member (Elected)
1. Founded by former TUBA members in November 2011 in Istanbul as an independent NGO to promote, practice, and uphold the principles of scientific merit, freedom, and integrity; officially recognized by ALLEA as an Academy of Science
2010  Executive Board Member (Elected), Biophysical Society
2008  Elected Council Member, Biophysical Society
2008  Elected Council Member, International Society of Quantum Biology and Pharmacology
2005  John K. Vries Endowed Chair, University of Pittsburgh.
2000  European Molecular Biology Organization (EMBO), Elected Member
1998  Excellence in Research Award, Bogazici University
1997  Turkish Academy of Sciences (TUBA)(*), Principal Member (Elected)
1. TUBA is a member of ALLEA (All European Academies)
1995  TUBITAK-TWAS Science Prize
1. TWAS: Third World Academy of Science
2. Turkish National Science and Technology Foundation (counterpart of NSF in Turkey)
1991  Sedat Simavi Physical Sciences Prize (joint with B. Erman)
1990  Chemistry Award for Young Scientists from TUBITAK (Turkish National Scientific and Technological Research Council)

        (*) Member of ALLEA (All European Academies)

Recent Professional Activities

2020 U of Pittsburgh Medical Center (UPMC) Children’s Hospital of Pittsburgh Children’s Neuroscience Institute (CNI). Executive Advisory Board Member. Pittsburgh, PA.
2020 National Institutes of Health (NIH) Common Fund’s Illuminating the Druggable Genome (IDG) Program Committee. External Program Consultant (EPC), Arlington, VA.
2020 The International Human Frontier Science Program (HFSP) Organization Scientific Consultant. From Research Proposal to Paradigm Shift: Supporting Frontier Research. Strasbourg, France.
2020 Academic Program Review Committee for the Dept of Quantitative and Computational Biology, U of Southern California. Los Angeles, CA.
2020 The Collaborative Computational Project for Biomolecular Simulation (CCPBioSim) External Advisory Board (EAB) Member. UK.
2020 The Heidelberg Institute for Theoretical Studies (HITS) HITS gGmbH Scientific Advisory Board “Molecular and Cellular Modeling (MCM)” Research Group Review Board. Heidelberg, Germany. Invited Reviewer.
2016 - 2020 NIH NLM Biomedical Informatics, Library, and Data Sciences Review Committee (BILDS) Chartered Member of Review Panel
2019- The National Institute of Health (NIH) Biotechnology Center for Macromolecular Modeling & Bioinformatics at The Beckman Institute, U of Illinois Urbana-Champaign, External Advisory Board Member.
2019- European Research Council (ERC) Starting Grant Review PE5 Panel Member, Brussels, Belgium.
2019 External Program Consultant (EPC) for the Illuminating Druggable Genome (IDG) Program, Common Fund/NIH Office of Strategic Coordination, NIH, Bethesda.
2019 Chair of the U of Pittsburgh Distinguished Faculty Committee
2019 The U of Pittsburgh/Carnegie Mellon University Pittsburgh Supercomputing Center Director Search Committee Member, Pittsburgh, PA.
2018-2019 The U of Pittsburgh, School of Medicine, Center for Systems Immunology Director and Faculty Search Committee Member
2018 17th European Conference on Computational Biology (ECCB), Program Committee and Symposium Chair, Athens, Greece.
2017 External Review Board Member, Computational Biology Program, College of Liberal Arts & Sciences, U of Kansas.
2017-present Associate Editor Proteins: Structure, Function, and Bioinformatics (Wiley)
2016- External Advisory Board Member for NIH funded Biomedical Technology and Research Resource (BTRR) Center for Biomolecular NMR Data Processing and Analysis, 1P41-GM111135-01A1 (PI: Jeffrey C. Hoch)
2016- U of Pittsburgh Chancellor’s Distinguished Research Award Committee.
2016 External Advisory Board Member for BCM Structural and Computational Biology and Molecular Biophysics Graduate Program, Baylor College of Medicine, Texas.
2015 "Innovate to Accelerate" online discussion forum via the NIH Common Fund, Member
2015 NIH NINDS Board of Scientific Counselors, Ad-hoc Member
2015 NIH -IMST-R, Pilot Centers for Precision Disease Modeling (U54) Study Section, Panel Member
2015 NIH Director's New Innovator Award, Editorial Review Panel Member
2015 - Editorial Board, Structure
2014 NIH Biomedical Technol & Res Centers (P41) Peer Review
2014 NIH Interdisciplinary Mol Sci and Training (IMST) Program Review
2014 NIH Study Section Chair, Special Emphasis Panel for Library of Integrated Network-Based Cell Signatures (LINCS): Perturbation-Induced Data & Signature Generation Centers (U54)
2014 - Editorial Board, Scientific Reports (Nature PBG)
2013 NIH Study Section Member, Special Emphasis Panel for Director's New Innovator Award (DP2)
2013 NIH Study Section Member for R15 Area Review
2011-present Editorial Board, Protein Science (Wiley-Blackwell)
2011  NIH Ad hoc Reviewer, EUREKA Proposals
2010  NIH Study Section Chair, IMST on Computational Biology, Image Processing, and Data Mining
2009  NIH Study Section Member, National Technology Centers for Networks and Pathways (TCNP), San Francisco
2008  Editorial Board, Proteins: Structure, Function and Bioinformatics
2008 - 2009  External Adv Board, Beckman Institute, Molec and Electric Nanostructures, U of Illinois, Urbana-Champaign
2007 - 2008  NIH Study Section Chair, Modeling and Analysis of Biological Systems (MABS)
2004 - 2007  NIH Study Section Member, Modeling and Analysis of Biological Systems (MABS)
2004 - 2007  Editorial Board, Biophysical Journal

Other Scientific Activities

10/2020  20th International Congress of IUPAB (International Union for Pure and Applied Biophysics), the 45th Annual SBBf (Brazilian Biophysical Society), and the 49th Annual SBBq (Brazilian Biochemistry and Molecular Biology Society) Meetings. Foz do Iguaco, Brazil. Invited Lecturer.
03/2020  "Chromatin Modeling: Integrating Mathematics, Physics, and Computation for Advances in Biology and Medicine". Research Center, Erwin Schrodinger International Institute for Mathematics and Physics (ESI) Vienna, Austria, Invited Speaker.
12/2019  University of Pittsburgh School of Medicine, Senior Vice Chancellors Laureate Lecture Series. Pittsburgh, PA. Invited Lecturer.
11/2019  The Cleveland Clinic Lerner Research Institute of Genomic Medicine Seminar Series; Cleveland, OH. Invited Lecturer.
09/2019  Biological Physics Mexico City 2019 Scientific International Conference, Mexico City, Mexico. Keynote Speaker
05/2019  National Institute of Health (NIH) National Institute on Drug Abuse (NIDA) Intramural Research Program (IRP) Seminar Series. Baltimore, MD, USA, Invited Speaker.
03/2019  63rd Annual Meeting of the Biophysical Society, Symposium on Glutamate Receptors. Baltimore, MD. Invited Speaker.
09/2018  Inaugural International Transmembrane Transporter Society (ITTS) Symposium. Vienna, Austria. Session Organizer and Speaker.
05/2017  2017 Workshop on Computational Biophysics and Systems Biology (CBSB2017), Cincinnati, OH. Keynote Speaker.
07/2016  National Strategic Computing Initiative Anniversary Workshop. The White House, Washington, D.C. Invited Speaker.

For a complete list of activities in 2004-2021, please see Conferences.

Memberships

2017-present  International Transmembrane Transporter Society (ITTS)
2009  Member, Center for Simulation and Modeling, Pitt
2008-present  American Society for Biochemistry and Molecular Biology (ASBMB)
2008-present  Society for Neuroscience (SfN)
2008  Member of the International Society of Quantum Biology and Pharmacology (ISQBP)
2006  Faculty, Ph.D. Program in Integrative Molecular Biology, Pitt
2005  Faculty, PhD Program in Structural Biology and Molecular Biophysics (MBSB-CMU/Pitt)
  Executive Committee Member, Integrative Systems Biology (ISB-Pitt)
  Executive Committee Member, Carnegie Mellon University/University of Pittsburgh PhD Program in Computational Biology (CPCB)
  Faculty, Peterson Institute of Nanoscience and Nanotechnology (NANO)
Faculty and Steering Committee, Molecular Biophysics and Structural Biology Ph.D. Program
2003  Member, Center for Biological Language Modeling, Carnegie Mellon University
2002  Faculty, UPMC McGowan Institute for Regenerative Medicine, Pitt
  Member, Molecular Medicine Institute, Pitt
  Faculty, Interdisciplinary Biomedical Graduate Program, School of Medicine.
2002-present  American Chemical Society (ACS)
Faculty, Biomedical Informatics Training Program, Pitt.
2001  Member of the International Society for Computational Biology (ISCB)
1999  Member of the Protein Society
1998  Member of the American Association for the Advancement of Science (AAAS)
1987-1997  American Chemical Society (ACS)

Grants/Awards

2020-2025  NIH - R01 Druggable Mitochondrial Targets for Treatment of Cerebral Ischemia. (PI- Clark, UPMC; Role: Co-I)
2020-2024  Controlling Monolysocardiolipin/Cytochrome C Peroxidase Complexes in Barth Syndrome (PI’s: Greenberg (Wayne State) and Kagan (Pitt))
2019-2024  NIH-NHLBI - P01 - Immunosuppression in Acute Lung Injury: Eroptosis as a Death Mechanism in Lung Injury (PI: Mallampalli, Ohio State U)
2012-2024  NIH-NIDDK - P01 - New Therapies for Liver Fibrosis and Hyperproliferation in Alpha 1-AT Deficiency (Comput Pharmacology Core PI; PI: Perlmutter, Wash U)
2009-2024  NIH-NIBIB - T32 - Integrated, Interdisciplinary, Comprehensive Inter-University Ph.D. Program in Comp Biology (CPCB) (Joint PI with Murphy, Russell, & Benos)
2012-2022  NIH-NIGMS - P41 - BTRC on High Performance Computing for Multiscale Modeling of Biol Systems (MMBioS) (PI: Bahar)
2010-2020  NIH-NIAID - U19 - Center for Medical Countermeasures against Radiation (CMCR) Signature-Directed, Sequential Delivery of Radiation Mitigators (Chemoinformatics Core E PI: Bahar); (PI: Greenberger, UPMC)
2014-2020  NIH-NIDA - P30 - NIDA Center of Excellence for Computational Drug Abuse Research (CDAR) (multiple PIs: Bahar, Xie and Xing)
2014-2019  NIH-NHGRI - U54 - BD2K (Big Data to Knowledge) Center for Causal Discovery (CCD) (multiple PIs: Bahar and Cooper)
2012-2016  NIH-NIGMS - R01, Continued Development of Protein Dynamics Software ProDy (PI: Bahar)
2009-2014  NIH-NIGMS - R01, Structural Dynamics of Biomolecular Systems
2009-2014  NIH-NCI – R01 Structure-based Design of Novel Small Molecule c-Myc Inhibitors (co-Investigator; PI: Prochownik)
2007-2013  NIH - NIMH - R01, Molecular Studies of Human CNS Transporters (co-Investigator; PI: Amara)
2003-2013  NIH-NLM - R01, Bridging Sequence Patterns and Structural Dynamics (PI)
2009-2014  NIH-NCI - R01, Structure-based Design of Novel Small Molecule c-Myc Inhibitors (co-Investigator; PI: Prochownik)
2011-2013  NIH- NCRR - UL1, Clinical & Translational Science Institute (Molecular and Systems Modeling Core co-Director, with Faeder and Benos)
2010-2012  NIH-NIGMS - U54, Membrane Protein Structural Dynamics Consortium (Computational Core co-Investigator; PI: Perozo)
2002-2010  NIH-NIBIB & NSF, Bioeng and Bioinformatics Summer Inst on Simulation & Comp Visualization of Biol Systems at Multiple Scales (PI: Bahar)
2004-2009  NIH-NCI - P01, Dendritic Cell Biology and Therapy (co-Investigator; PI: Finn)
2005-2008  NIH-NIGMS - R33, Computational Prediction of Biomolecular Dynamics
2005-2008  NIH- NIMH - U54, Pittsburgh Molecular Libraries Screening Center (Bioinformatics Core PI; PI: Lazo)
2003-2007  NIH-NIGMS - P20, Multiscale Dynamics of Cell Control and Apoptosis (PI: Bahar)
2002-2007  NSF-ITR, Computational Learning and Discovery for Protein Sequence, Structure & Function Mapping (co-Investigator; PI: Reddy)

Publications

For a PDF of Dr. Bahar’s full CV, please contact Anna Reinhard anr189@pitt.edu