Bahar Lab

Dr. Ivet Bahar
John K. Vries Chair in Computational & Systems Biology
Department of Computational & Systems Biology
School of Medicine, University of Pittsburgh
3064 Biomedical Science Tower 3
3501 Fifth Avenue, Pittsburgh, PA 15213

Voice:	412 648 3332
Fax:	412 648 3163
email:

Research Interests
Biomolecular systems dynamics at multiple scales; evolution of proteins' sequence, structure, dynamics and function; computer-aided drug discovery and polypharmacology; network models for protein-protein interactions, supramolecular machinery and allostery; modeling and simulations of membrane proteins dynamics and mechanisms of interactions.

Congratulations to Lidio Meireles, Ying Liu, and Lin Liu on their successful defenses!

Lidio was first author on the Protein Science article that became the cover of the September 2011 issue, "Pre-existing soft modes of motion uniquely defined by native contact topology facilitate ligand binding to proteins", along with lab members Dr. Mert Gur, Dr. Ahmet Bakan, and Dr. Ivet Bahar.

Publications 2011

"ProDy: Protein Dynamics Inferred from Theory and Experiments" Bakan, A., Meireles, L., & Bahar, I. (2011). Bioinformatics 2011. PMID: 21471012

"Protonation of Gultamate-208 Induces the Release of Agmatine in an Outward-Facing Conformation of Arginine/Agmatine Antiporter" Elia Zomot and Ivet BaharJ Biol. Chem. (2011). Epub ahead of print. PMID: 21487006